The present study was carried out to determine the effect of dietary ginsenosides and ginseng supplementation on productive performance, physiological and immunological parameters in Gimmizah chickens. A total number of 210 (189 laying hens and 21 cocks) at 32weeks of age, were randomly divided into 7 treatment groups. Each treatment represented by 3 replicates each containing 9 hens and 1 cook. The first group was fed the basal diet without supplementation (control). While, the second, third and fourth groups were fed the basal diet supplemented with ginsenosides (GnD) at 100, 200 and 300 mg/kg diet, respectively. The fifth, sixth and seventh groups were fed the basal diet supplemented with ginseng (Gn) at 100, 200 and 300 mg/kg diet, respectively. All birds received feed and water ad-libitum throughout the experimental period (32 -44 weeks of age). Results obtained showed that: The chickens fed the basal diet supplied with 300 mg Gn/kg diet had significant results for egg production, egg mass, feed conversion ratio, and fertility percentage compared with those in the other experimental groups. Supplementation of chicken's diet with GnD and Gn significantly improved antioxidant status and significantly increased estrogen and progesterone hormones concentrations compared to control group. In conclusion, supplied Gimmizah chickens diet with ginseng or ginsenosides at 300 mg/kg diet improved productive and reproductive performance and the immune status during laying period.