This work was aimed to study the effect of zeolite (Clinoptiolite) addition on productive performance and blood constituents of broiler chickens drank saline well water (3398 ppm total dissolved solids, TDS). A total number of 120 broiler chicks one day – old unsexed Ross 308 (body weight of 40.09 g ± 0.11). Chicks were randomly separated to four equal treatments (30 chicks of each) which in turn separated to three equal replicates (10 chicks each). The 1^st treatment (T1), chicks drank tap water containing 265 ppm TDS with basal diet. The 2^nd treatment (T2), chicks drank saline well water containing 3398 ppm TDS with basal diet. The 3^rd treatment (T3) and the 4^th treatment (T4) chicks drank saline well water containing 3398 ppm TDS with basal diet + 3 % zeolite and + 6 % zeolite, respectively.

Final body weight, total weight gain and feed conversion of broiler chickens were significantly enhanced in control group (T1), T3 and T4 as compared with the chickens in T2.  On the other hand, the total feed intake significantly decreased in the chickens of T4 as compared with T1 and T2, while, the total water intake significantly increased in T2 compared with other treatments. Carcass weight percentage was significantly increased in the chickens of T1, T3 and T4 treatments as compared to T2. Red blood cells, hemoglobin and packed cell volume were increased (P<0.05) in the chickens of T3 when compared to T2. Albumin level was significantly increased in T4 compared with other treatments. Creatinine, Alanine and aspartic transaminase concentrations were increased (P<0.05) in the chickens drank saline well water (T2) as compared to other treatments. On the other hand, glucose and cholesterol levels significantly decreased in the chickens of T2 as compared to T1, T3 and T4.
In conclusion, adding 3 % zeolite in broiler chickens diets might enhance the productive performance and some hemato-biochemical parameters under drinking saline well water conditions.