The objective of the present study was to investigate the synergism relationship between xylanase (Xyl.) and pectinase (Pec.) enzymes when applied in different levels of metabolizable energy (ME) broiler diets based on corn-soybean meal. The study included two experiments. Experiment1 (EXP1) studied the effects of Xyl. and/or Pec. supplementation to corn-soybean standard diet. Experiment 2 (EXP2) examined the enzymes supplemented to different reduced ME diets (lower 100 kca/kg, NC100; and lower 150 kcal/kg, NC150) than control. Growth performance, carcass characteristics, and meat quality of broiler were carried out. The obtained results were: EXP1 showed that enzymes supplementation (Xyl., Pec. or both of them) to broiler diets resulted in significant improvement of body weight (BW), body weight gain (BWG), feed conversion ratio (FCR) and breast meat yield%, while feed intake (FI) were decreased. Enzyme combinations (Xyl. and Pec.) improved dressing percentage, also lead to significant improvement in total protein (TP) of broiler meat, whereas the individual enzyme had no effect. EXP2: Reducing ME values from normal to NC150 level caused significant reduction in final BW, BWG, carcass edible parts percentage, MDA and TP of broiler meat, and cause significant increase in FI and drip loss of breast meat and drum stick samples percentage of broiler meat. The combination of Xyl. and Pec. supplemented to NC100 and NC150 diets significantly improved growth performance more than the individual enzymes, while, the best FCR was recorded in NC100 supplemented with the combination of Xyl. and Pec. enzymes. The NC150 supplemented with Xyl. and Pec. showed better carcass total weights and dressing percentage compared with other treatments, and the lowest abdominal fat recorded in NC100P. and NC150. In conclusion, the combination of Xyl. and Pec. is more effective than the individual in growth performance and quality of carcass and meat.