The present study was conducted to evaluate the effects of propolis, bee-pollen and bee-venom as eco-friendly alternative on productive and physiological performance of broiler chickens. A total of 408 unsexed one week old, Cobb 500 broilers were randomly divided into 8 experimental treatments (3 replicate, 17 chicks each). The first treatment was fed basal diet without any additives and served as a control. The second treatment was fed the basal diet supplemented with the growth promoter Biox-Y^® 0.5g per kg of diet. The third and the forth treatments were fed basal diet supplemented with propolis (200 or 400 mg/kg diet). The fifth and the sixth treatments were fed basal diet supplemented with bee-pollen (1 or 2 g/kg diet). The seventh and the eighth treatments were fed the basal diet and their water was supplemented with bee-venom (1or 2 mg/L water). Weekly body weight, body weight gain, feed intake and feed conversion ratio obtained. Blood samples were obtained at the end of the experiment (7 weeks of age) to determine blood parameters. The obtained results showed that the chicks fed diet with propolis (400 mg/kg diet) had significantly higher body weight and total body weight gain compared to the control treatment. Also, all treated treatments had significantly lower average daily feed intake during the whole experimental interval and significantly improved total feed conversion ratio compared to the control and Biox-Y^® treatments. The chicks fed diets containing propolis (200 or 400 mg/kg diet) or bee-venom (2 mg/L water) or bee-pollen (2 g/kg diet) showed significantly lower plasma cholesterol and LDL-cholesterol concentration compared to the control and Biox-Y^® treatments. Consequently, propolis (200 or 400 mg/kg diet) treatments and bee-pollen (2 g/kg diet) treatment had significantly higher plasma HDL cholesterol concentration than the control treatment. Broilers fed propolis (200 or 400 mg/kg diet) for 6 weeks had significantly lower serum AST and ALT concentrations compared to the control treatment. The chicks fed diet with propolis (400 mg/kg diet) showed significantly higher plasma T3, T4 concentration or T3/T4 ratio compared to the control treatment.