Purpose: The aim of this study was to compare fracture resistance of provisional restorations fabricated with conventional manual procedure, CAD/CAM milling and 3D Printing techniques. Materials and Methods: one human upper first premolar was prepared and duplicated using epoxy resin to produce twenty one dies. Accordingly, a total of (N=21) provisional crowns were constructed. The Constructed provisional restorations were divided into 3 groups according to the method of construction (n=7 for each group), Group 1: Provisional crowns were constructed using conventional manual technique, Group2: Provisional crowns were constructed using CAD/CAM milling technique, Group3: Provisional crowns were constructed using 3D Printing technique. All Provisional crowns were bonded to their corresponding epoxy resin dies by using CharmTemp ZONE temporary cement and subjected to thermocycling procedure simulating approximately one month of clinical situations Results: Statistical analysis showed that the fracture resistance of CAD/CAM samples (group 2), recorded the statistically significant highest mean fracture resistance value (910.20 ± 118.95), followed by 3D Printing samples (group 3) (720.80 ± 129.57), while the lowest value was recorded for Conventional samples (group 1) (626.71 ± 103.23). ANOVA test showed that there was no significant difference between 3D Printing samples (group 3) and Conventional samples (group 1). Conclusion: CAD/CAM provisional crowns have superior strength than 3D Printing and conventional crowns.