Purpose: This study was conducted to evaluate the effect of egg shell and white tea dentin pre-treatment on microtensile bond strength between resin composite and dentin surface. Materials and Methods: Forty-five extracted molar teeth were divided into three subgroups according to dentin pretreatment ; with no treatment (control ), Egg shell, and white tea. Each group was subdivided for microtensile testing into three equal subgroups, either after 24 hours (T0), after1 month (T1), and after 3 months (T2). The occlusal enamel was removed. And according to each group one of pretreatments was used. Resin composite blocks were fabricated on dentin after application of self etch adhesive. The teeth were longitudinally sectioned to get composite-dentin beams, two central beams were selected from 45 teeth in order to have 90 beams. Specimens were assessed after 2 storage periods in artificial saliva: either one month (T1) or three months (T2) storage period. Specimen were subjected to microtensile bond strength testing. Results: at T0, there was no statistically significant difference in mean μTBS between different dentin pre-treatments, while at T1 and T2, white tea group showed significantly the highest μTBS mean values, followed by egg shell group, then control group. Conclusion: Natural remineralizing agents could enhance microtensile bond strength of universal bonding system in self etch mode, and remineralizing potential of natural agents has stabilized by time.