Purpose: This study aimed to evaluate the effect of rapid prototyped upper complete denture on retention and patient satisfaction. Material and methods: Eight completely edentulous patients were selected for this study with ages ranged from 40-50 years. All patients had received two complete dentures one fabricated by conventional heat compressed method and the other fabricated by rapid prototyping technology. Patients were classified into two groups, four patients each. Group I received the conventional denture first then the rapid prototyped denture while, Group II received the rapid prototyped denture first then the conventional denture. All patients were instructed to wear their dentures for equal periods of 1 month where retention and patient satisfaction were measured at insertion and after 1 month. After an interval of two weeks, as a wash out period, patients received their other denture. Results: The results of this study showed that there was a high statistical significant difference between the conventional and the rapid prototyped denture regarding retention and patient satisfaction while there was no significant difference between both groups, group I which received the conventional denture first and group II which received the rapid prototyped denture first. Conclusion: within the limitation of this study, it was concluded that retention and patient satisfaction of maxillary rapid prototyped denture were significantly higher than that of the conventional denture. The rapid prototyped dentures can be used as an alternative effective satisfactory treatment for completely edentulous patients rather than conventional dentures but furthermore studies are needed.