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141989

Evaluation of 3D Printed Computer Assisted Patient’s Specific Scaffold Seeded by Autologous Bone Marrow Mononuclear Cells in Mandibular Reconstruction

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Oral and Maxillofacial Surgery

Abstract

Purpose: This study was carried out to evaluate both clinically and radiographicly the use of 3D printed computer assisted patient's specific scaffold seeded with ABMMCs in mandibular reconstruction. Materials and methods: The present study was conducted on eight patients who needed mandibular reconstruction. All patients in this study were subjected to mandibular reconstruction using 3D printed computer assisted patients specific scaffold using PLLA scaffold seeded with ABMMCs combined with osteoplastic materials of biological origin as Osteomatrix (LLC Konectbiopharm, Russia) which composed of natural collagen and hydroxyapatite with affinity-bound sulfated glycosaminoglycan (SGAG). All patients underwent preoperative cranial-maxillofacial CT scans, immediate postoperative and after six months for assessment of bone density and volume changes. Results: The reduction in bone density (17.4%) and bone volume (14.5%) from immediate to six months was statistically significant. There was an increase in bone density in the area near the autogenous bone of the patient than the area far from the autogenous bone of the patient. Conclusion: Using 3D printed computer assisted patient's specific scaffold seeded with ABMMCs combined with Osteoplastic materials of biological origin in mandibular reconstruction is useful in small defects.

DOI

10.21608/adjg.2021.23389.1237

Keywords

Mandibular reconstruction, Poly (L-lactide) lactic acid, 3D printed

Authors

First Name

Wafaa

Last Name

Mohammed

MiddleName

A.

Affiliation

Demonstrator of Oral and Maxillofacial Surgery, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt.

Email

wafaaanwar89@yahoo.com

City

Cairo

Orcid

-

First Name

Suzan

Last Name

Hassan

MiddleName

A.

Affiliation

Professor of Oral and Maxillofacial Surgery, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt.

Email

sabdelhakim2003@yahoo.com

City

Cairo

Orcid

-

First Name

Hatem

Last Name

ALahmady

MiddleName

H.

Affiliation

Professor of Oral and Maxillofacial Surgery and Head of Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt.

Email

dr_alahmady@hotmail.com

City

Cairo

Orcid

-

First Name

Wael

Last Name

Shawkat

MiddleName

M.

Affiliation

Head of Oral and Maxillofacial Surgery Department, Health insurance hospital, Cairo, Egypt.

Email

weal_2003@yahoo.com

City

Cairo

Orcid

-

First Name

Ahmad

Last Name

Abd Elazeem

MiddleName

F.

Affiliation

Assistant researcher of regenerative medicine and genetics, Oro-dental Genetics Department, Human Genetics Division, National Research Center, Cairo, Egypt.

Email

faroukahmed@hotmail.com

City

Cairo

Orcid

-

First Name

Ibrahim

Last Name

ELsharabasy

MiddleName

M.

Affiliation

Consultant of Oral and Craniomaxillofacial Surgery.

Email

ibrahimelsharabasy@gmail.com

City

Damietta

Orcid

-

First Name

Ismail

Last Name

Nazif

MiddleName

O.

Affiliation

Electrical and Medical 3D Printing Engineer.

Email

i.nazif@rubik3d.com

City

cairo

Orcid

-

Volume

8

Article Issue

1-B

Related Issue

20980

Issue Date

2021-01-01

Receive Date

2020-02-23

Publish Date

2021-01-01

Page Start

109

Page End

115

Print ISSN

2537-0308

Online ISSN

2537-0316

Article File

ADJG_Volume 8_Issue 1-B_Pages 109-115.pdf

PDF . 403.7kB

Link

https://adjg.journals.ekb.eg/article_141989.html

Detail API

https://adjg.journals.ekb.eg/service?article_code=141989

Order

14

Type

Original Article

Type Code

488

Publication Type

Journal

Publication Title

Al-Azhar Dental Journal for Girls

Publication Link

https://adjg.journals.ekb.eg/

MainTitle

Evaluation of 3D Printed Computer Assisted Patient’s Specific Scaffold Seeded by Autologous Bone Marrow Mononuclear Cells in Mandibular Reconstruction

Details

Type

Article

Created At

22 Jan 2023