Purpose: This study was carried out to evaluate root surface changes and bone density accompanying two different methods of accelerated orthodontic tooth movement by Cone beam computed tomography (CBCT). Patients and methods: The present study was applied to twenty patients. With bimaxillary dento-alveolar protrusion or Angle Class II Division 1 malocclusion. The line of treatment was the extraction of the upper first bicuspids and then cuspid distalization. The patient's sample was divided into two equal groups. In the group I, one side of the maxillary arch was chosen for treatment with peizocision, and in the group II, injectable platelet-rich fibrin (i-PRF) injection was used. The opposite sides in two groups acted as controls. Canine distalization was performed in both sides by 150 gm. of force applied from nickel titanium closed coil spring. The following parameters were measured from cone-beam tomography: volumetric root length and bone density.Besides this, the canine retraction rate was measured from casts Results: The canine retraction rates were greater in experiential sides than in the control sides in the two groups. Decrease volumetric root length and bone density were recorded in both groups after canine retraction Conclusions: Piezocision technique and i-PRF injection are efficient procedures that reduce the time needed for canine distalization. No significant differences regarding volumetric root resorption were observed in both groups between the experiential side and the control one after canine retraction.