Purpose: The intent of the study was to compare the periodontal and bony changes of piezocision corticotomy with bone graft guided by 3D-surgical template in maxillary protrusion versus non grafted one. Patients and Methods: Prospective study included 20 maxillary protrusive female patients with age group ranging between 20 and 50 years. Patients were divided in to group I: treated with piezocision corticotomy without bone graft guided by 3D surgical template. Group II: treated with piezocision corticotomy with bone graft guided by 3D surgical template. CBCT scan was performed of all the patients. Gingival index (GI), probing depth (PD) and CBCT images were performed at baseline and 6months then collected data were analyzed using SPSS statistical analysis program. Results: There were significant reductions in GI, and PD of Group I and Group II from baseline to 3 months. Radiographic analysis of group II showed a statistically significant increase of labial bone thickness (LBT) after 6 months. Conclusion: The uses of guided bone regeneration during cortioctomy improve the clinical parameter and augment the labial bone with minimal loss of bone thickness during en-mass movement.