Purpose: The aim of the study was to evaluate and apply a minimal invasive approach for reconstruction of atrophic maxilla using computer-guided implant surgery by zygomatic implants combined with conventional implants. Material and methods: 10 patients with severely atrophic edentulous upper arch were included in this study, each patient had 2 conventional implants placed in the anterior maxilla, and 2 zygomatic implants on either sides placed in the zygomatic bone. In all patients a computer guided approach using a computer guided stent was used for drilling the conventional and zygomatic implants. All patients followed a clinical and radiographic follow up Result: Zygomatic Implants success was 90.0% while conventional implants success was 80.0%. The mean ± standard deviation values of coronal deviation were 3.24 ± 1.9 mm for Zygomatic implants and 2.9 ± 2.5 mm for conventional implant. The mean ± standard deviation values of apical deviation for were 4.2 ± 2.5 mm for zygomatic implants and 2.6 ± 2.5 mm for conventional implants. The mean ± standard deviation values of bone implant contact for zygomatic implant were 19.5 ± 5.3 mm, the bone covering the zygomatic implant laterally were 6 ± 2.3 mm, the minimum distance from the orbit were 5.6 ± 3.2 mm. General satisfactions for the treatment was 8.6. Conclusion: The use of zygomatic implants combined with conventional implants using virtual computer guided planning and surgery was useful for reconstruction of atrophic maxilla allowing an accurate, safe, graft less, less invasive surgery and provided a high patient satisfaction.