Purpose: The aim of the study was to assess microbial adherence on maxillary complete denture carried by different fabrication techniques; the conventional and CAD/CAM ( computer-aided design and computer-aided manufacturing) techniques.
Material and methods : Ten completely edentulous patients were selected and divided into randomly two equal groups: group I, patients received maxillary and mandibular complete dentures made of conventional heat-cured acrylic resin and group II, patients received maxillary CAD/CAM complete denture and mandibular conventional complete denture. Assessment of the microbial colonization of maxillary dentures for both groups was carried out after 3, 6 and 9 months after denture insertion. The tested microorganisms are Candida albicans (C. albicans), Staphylococcus aureus (S. aureus), Streptococcus mutans (S. mutans) and Escherichia coli (E. coli).
Results: Comparison of microbial colonization count represented in colony forming unit per ml (CFU/ml). Change between group I and group II revealed that, group II has statistically significant lower CFU/ml than group I for all the tested microorganisms during the study period (P-value <0.05) except for E. coli after 3 months the difference between both groups was statistically non significant (p = 0.139). And there was a gradual increase in the microbial count during the time of using both types of dentures.
Conclusion: CAD/CAM dentures showed less microbial colonization than conventional heat cure acrylic resin dentures. Further short-term and long-term clinical studies are needed to validate CAD/CAM technology in complete denture prosthodontics.