Beta
ManageSearchChatDiscover
17152

Evaluation of Subantimicrobial Dose Doxycycline Effects on Dental Implant Osseointegration in Type II Diabetic Patients

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Oral Medicine and Periodontology

Abstract

Objective : The present study was carried out to compare radiographic outcomes of dental implant in type II diabetic patients with or without adjunctive administration of subantimicrobial dose doxycycline.   Subjects and Methods : This study included 20 patients with controlled type II diabetes mellitus of both genders, their age ranged from 40-48years.The study groups were designed in two groups, test group treated with dental implant with systemic administration of subantimicrobial dose doxycycline(SDD) for twice per day for 3 months and control group received dental implant alone.   Results: Regarding radiographic marginal bone levels measurements; in both groups the mean marginal bone loss increased by time, with significant difference between both groups where the test group (SDD received group) showed the lower marginal bone loss values. In both groups, bone density measurements increased by time, with significant percentage change recorded for test group (SDD received group) 55.22% while control group recorded 17.40% from base line values. Conclusions: The use of sub-antimicrobial dose doxycycline with dental implants in type II diabetic patients was effective as an adjunctive host modulatory drug. Systemic administration of subantimicrobial dose doxycycline with dental implants in type II diabetic patients resulted in greater increase in bone density and less marginal bone loss thus subantimicrobial dose doxycycline can enhance the osseointegration of dental implants.

DOI

10.21608/adjg.2018.17152

Keywords

Diabetes mellitus, Subantimicrobial dose doxycycline, dental implant, Cone beam computed tomography

Authors

First Name

Nora

Last Name

Abdel Rahman

MiddleName

-

Affiliation

Associate Lecturer of Oral Medicine, Periodontology, Oral diagnosis and Radiology Department. Faculty of Dental Medicine for Girls. Al-Azhar University.

Email

-

City

-

Orcid

-

First Name

Ossama

Last Name

Al Shal

MiddleName

-

Affiliation

Professor of Oral Medicine, Periodontology, Oral diagnosis and Radiology Department, Vice- Dean for Postgraduate Studies. Faculty of Dental Medicine for Girls. Al-Azhar University.

Email

-

City

-

Orcid

-

First Name

Olfat

Last Name

Shaker

MiddleName

-

Affiliation

Professor of Bio-Chemistry. Faculty of Medicine. Cairo University.

Email

-

City

-

Orcid

-

First Name

Mai

Last Name

Shafik

MiddleName

-

Affiliation

Associate Professor of Oral Medicine, Periodontology, Oral diagnosis and Radiology, Department. Faculty of Dental Medicine for Girls. Al-Azhar University.

Email

-

City

-

Orcid

-

Volume

5

Article Issue

3

Related Issue

3615

Issue Date

2018-07-01

Receive Date

2018-10-21

Publish Date

2018-07-01

Page Start

225

Page End

235

Print ISSN

2537-0308

Online ISSN

2537-0316

Article File

ADJG_Volume 5_Issue 3_Pages 225-235.pdf

PDF . 264.1kB

Link

https://adjg.journals.ekb.eg/article_17152.html

Detail API

https://adjg.journals.ekb.eg/service?article_code=17152

Order

2

Type

Original Article

Type Code

488

Publication Type

Journal

Publication Title

Al-Azhar Dental Journal for Girls

Publication Link

https://adjg.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023