Objectives: This study was conducted to evaluate the remineralization potential of grape seed extract versus amorphous calcium phosphate nanoparticles on sound and caries affected dentin.
Materials and methods: Grape seed extract powder (GSE) was added to Clearfil SE primer with a concentration of 0.5 wt% to obtain primer + GSE while nanoparticles of amorphous calcium phosphate (NACP) were incorporated into the Clearfil SE adhesive at mass fractions of 20% to obtain adhesive + NACP. Class V cavity preparation was prepared on the anterior teeth of fifteen white rabbits. Rabbits were divided into three main groups according to the type of material used Group A (primer + GSE) Group B (adhesive + NACP), Group C (sodium fluoride NAF as positive control).
Each group was subdivided into two subgroups according to type of substrate in which right side was act as sound dentin while left side was act as artificial caries affected dentin. After 10 days the dentin was examined using EDX analysis to determine amount of calcium and phosphorus in each sample. Results: There was no statistically significant difference between mineral content of different materials compared with positive control group for both sound and caries affected dentin. Conclusion: - Grape seed extract and nano amorphous calcium phosphate