Objectives: evaluate malocclusion severity in Egyptian children having cleft lip and/ or palate. Material and Methods: A sample of 100 Egyptian children. Fifty children representing the cleft lip and /or palate (Group I) and another fifty children
free from any systemic disease representing the control group (Group II). Both sexes male and female were included with age ranged from (4 – 15 Years). Each child had subjected to personal data, medical history, assessment of oral health knowledge, attitudes towards dental care, oral health assessment and statistical analysis using SPSS 17. Results: 11 patients (22%) had definite malocclusion, 15 patients (30%) had severe malocclusion, while 14 patients (28%) had very severe maocclusion. On the other hand, 41 (82%) of the patients in the control group had no abnormalities or normal occlusion. Fisher's exact test revealed that the difference between both groups was statistically significant, except in case of definite malocclusion. Conclusion: The children having cleft lip and / or palate had severe malocclusion and they would need comprehensive orthodontic treatment.