The facilities offered by the distributed computing systems such as Internet of Things (IoT), multi-agent systems (MASs) and
vehicular networks can be used to integrate such paradigms to provide several services of Internet of Vehicles (IoV). The core
objective of this paper is to present the integration of Multi-agent Systems (MASs) with IoT and IoV as a new model in Cypher
Physical System (CPS) of smart vehicles application. MASs are more effective when we employ them with distributed computing
infrastructures as with IoV to achieve more high performance. On the other hand, there is a lack of research works and a few papers
in the literature till today with the integration of such paradigms, MAS, IoT, and IoV. The features of the proposed integration are
based on the main characteristics of intelligent agents like intelligence, flexibility, proactivity and reactivity, and autonomy which
can be employed in IoV paradigm to provide new solutions and intelligent services that will explore new advances and different
facilities in transportation problems. Also, IoT provides an adequate environment for communication with MASs paradigms and
applications as it provides reliable, flexible, effective, and smart services to vehicular networks. Moreover, integrating MASs with
IoT and IoV could provide flexible, autonomous, and intelligent services of IoV. Some limitations and challenges of the proposed
integration method in this paper are presented with some future research trends.