Background: Anastomotic leakage is one of the most feared complications after colorectal surgery. This study aiming at studying the effect of different operative risk factors on incidence of leakage post colorectal cancer surgeries.
Method: This is retrospective study of 340 patients with colorectal cancer who underwent resection anastomosis, at the department of Surgery, South Egypt Cancer Institute, Assiut University between January 2005 till December 2016, and the data were collected from archive and cancer registration data base of surgical oncology department. Results: Prophylactic stoma done in 82 patients, In (12.6%) of patients ;- anastomosis done by stapler, in 7.6% of patients surgeries operated laparoscopically .In (22.4%) contamination of operative field occurred, the most frequent type of anastomosis was colo-anal anastomosis , the most frequent surgery was anterior resection of Dexon. Conclusion: studying the effect of operative risk factors on incidence of leakage may help in decision making intra operative regarding type of surgery, approaches and techniques used aiming at decrease the leakage.