Background: Chronic otitis media (COM) endures be an important health problem across the world. Unleashed usage of antibiotics caused development of resistant bacterial strains for infections such as COM as well. Useful antibiotics therapy should be selected according to especially susceptibility pattern of most common local organisms.
Aim: The study was conducted from July 2018 to June 2019 in one referral otolaryngology surgical center in the south of Iran to determine the causative microorganisms, their antibiotic sensitivity pattern and occurrence of bacteremia in chronic otitis media patients undergoing tympanomastoidectomy.
Patients and Methods: This study designed with eighty-seven samples from eighty- seven ears which were obtained from patients who suffer from chronic otitis media. aerobic culturing and antibiotic sensitivity testing were done with standard antibiotic discs using the National Committee for Clinical Laboratory Standards guidelines. Also, venous blood samples were taken before and after the operation for microbiological study. fun Chi-square test, t-test were used for the statistical analysis in this study.
Results: No microorganisms were isolated from the preoperative and post-operative blood cultures. Out of 87 patients, microbiological culture was yielded from 51 specimens (58.6 %). Staphylococci coagulase negative (n=19, 37%) was the most common isolate followed by Staphylococci coagulase positive (n=12, 23%). Susceptibility pattern of Staphylococci spp. showed that almost 80% isolates were sensitive to Ciprofloxacin followed by almost 60% to Co-trimoxazole.
Conclusion: Our results proposed that bacteremia might not happen after tympanomastoidectomy. Continuous investigation of susceptibility pattern can improve the success of treatment process for chronic otitis media.