Solitary Fibrous Tumors (SFTs) are relatively rare benign neoplasms that commonly occur in the pleura and barely reported in parapharyngeal space. SFT is often misdiagnosed due to its microscopic resemblance to several other spindle cell tumors; however, there are specific diagnostic features on MRI and immunohistochemical.
We herein report a case of a 65-year-old male patient with SFT arisen in the parapharyngeal space completely resected through a transoral approach. Also, a comprehensive review of previously published cases and case series of parapharyngeal space SFTs and hemangiopericytoma (HPC) reported globally in English up to August 2018 using the PubMed/Medline databases was presented. In addition to the current case, there are thirteen SFTs and thirteen HPCs reported cases. All cases were presented and analyzed. Males are predominantly affected. Actually, 23% of HPCs reported cases presented with the histological indicator of aggressive behavior while none of SFTs reported cases. Thus, Parapharyngeal space SFT presented herein is the first case that had been completely resected using the transoral technique. Hemangiopericytoma is a cellular form SFTs; it seems to behave more aggressively than SFTs from studying the previously reported cases