Background: Chronic rhinosinusitis has a great impact on the quality of life. Functional endoscopic sinus surgery is the treatment of choice for chronic rhinosinusitis refractory to medical treatment as it allows restoring ventilation and mucociliary clearance. Sino- Nasal Outcome Test 22 questionnaire has been used for evaluating changes in symptoms and predicting the extent of postoperative outcome.  Objective: The aim of the study was to evaluate how functional endoscopic sinus surgery affects the outcome in patients' symptom profile and quality of life.
Patients and Methods: 60 patients indicated for functional endoscopic sinus surgery from March 2017 till December 2018. This prospective study was carried out at the Otorhinolaryngology Department at El-Menoufia University Hospital. For all patients, the Sino-Nasal Outcome Test–22 was completed before and three months after Functional Endoscopic sinus surgery.  Results: 60 patients were enrolled in this study (34 Males and 26 Females) aged from 25 to 40 years old with a mean age of 32.9 ± 5.3. The results of the statistical analysis showed that functional endoscopic sinus surgery reduced the Sino-Nasal Outcome Test–22 questionnaire score with a statistically high significant result (P ≤ 0.001).
Conclusion: Functional endoscopic sinus surgery statistical significant improvements in disease-specific quality of life for patients with chronic rhinosinusitis