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195502

Dosimetric evaluation of physical parameters for different energies in advance radiotherapy technique for Liver cancer

Article

Last updated: 22 Jan 2023

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Abstract

ABSTRACT
Introduction: This work aimed to study dosimetrically compare 6MV, 10MV and dual energies (DE) photon beam energies in liver cancer, evaluating the effect of using different of energies on intensity-modulated radiation (IMR) outcome were selected.IMRT treatment plans Identical optimization constraints were applied for all energy plans. The parameters like beam angle, number of beams, were kept constant to achieve the same clinical objectives. Both qualitative and quantitative methods were used. many physical indices for Planning Target Volume (PTV), the relevant Organs at Risk (OARs) as mean dose (Dmean), maximum dose (Dmax), 95% dose (D95), integral dose, total number of segments, and also the number of monitor unit (MU) were applied.
Materials and methods: 28 virtual IMRT treatment planning were involved in this study. Step-and-shoot IMRT treatment plans were designed. Plans depended on Monaco (IMRT) treatment plan outcome. For each case, three plans with the same beam geometry were created using 6 MV, 10 MV and DE. For dual energy plans, all cases were optimized with identical planning objectives and normalized such 98% of the target received 100% of prescription dose.
Results: The three techniques showed comparable PTV inhomogeneity and conformity for all patient's differences within the median values <0.6%10 MV and DE plans also additionally a statistically important reduction in the total number of monitor units (MU) of 14.2% (p <0.01) and 13.3% (p <0.01) as compared to 6 MV, respectively.
Conclusion: Each dual energy and 10 MV energy had similar PTV dosimetry characteristics.

DOI

10.21608/ajnsa.2021.60437.1441

Keywords

6-MV, 10-MV, Double Photon Energies, Intensity-Modulated Radiation Therapy (IMRT) photon energy, cancer

Authors

First Name

Sherihan

Last Name

Hassan

MiddleName

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Affiliation

National Cancer Institute (NCI), Cairo University, Cairo, Egypt

Email

shhassan148@yahoo.com

City

-

Orcid

0000-0003-3304-0781

First Name

arafa

Last Name

aly

MiddleName

-

Affiliation

Physics department, faculty of sciences, Beni-Suef University, Egypt

Email

arafaaly@aucegypt.edu

City

Beni Suef

Orcid

0000-0003-0795-378X

First Name

Khaled

Last Name

Elshahat

MiddleName

-

Affiliation

Medical Radiation Physics - Al Azhar University

Email

khaled_elshahat@azhar.edu.eg

City

-

Orcid

-

First Name

Mostafa

Last Name

Eissa

MiddleName

-

Affiliation

Nuclear and Radiation Physics Research Laboratory, Physics Department, Faculty of Science, Beni-Suef University,

Email

mostafa.eisa@science.bsu.edu.eg

City

-

Orcid

-

Volume

54

Article Issue

4

Related Issue

27948

Issue Date

2021-10-01

Receive Date

2021-01-31

Publish Date

2021-10-01

Page Start

147

Page End

156

Print ISSN

1110-0451

Online ISSN

2090-4258

Link

https://ajnsa.journals.ekb.eg/article_195502.html

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https://ajnsa.journals.ekb.eg/service?article_code=195502

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Original Article

Type Code

455

Publication Type

Journal

Publication Title

Arab Journal of Nuclear Sciences and Applications

Publication Link

https://ajnsa.journals.ekb.eg/

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Article

Created At

22 Jan 2023