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Replacement of Cobalt in Medical Device Sterilization: Current Trends, Opportunities and Barriers to Adoption of X-ray and E-Beam Within the Medical Device Sterilization Market

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Last updated: 03 Jan 2025

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Abstract

Radioactive sources, specifically Co-60, are crucially important to the medical device sterilization industry; however, their benefits must be balanced against the need to ensure that the materials are secure. Accelerator-based sterilization methods, including X-ray and E-Beam, can in many cases sufficiently replace Co-60 and ethylene oxide, the dominant modalities currently in use; however, a lack of hands-on experience with accelerators, regulations, and a lack of capacity have hampered faster adoption of these technologies. The market is likely to change, however, given public pressures against ethylene oxide and concerns over the cost and long-term supply chain robustness of Co-60. This may provide an opportunity for growth for accelerator capabilities. Current research at Sandia National Laboratories and Argonne National Laboratory, on behalf of the Department of Energy's National Nuclear Security Administration Office of Radiological Security, is focused on developing an understanding of the medical device sterilization marketplace, the different modalities that are used to sterilize goods, and the drivers that affect the actors within it. Research at Pacific Northwest National Laboratory, in conjunction with the medical device sterilization industry, has focused on expanding the industry's understanding of the capabilities of X-ray sterilization and developing data that can inform the industry's consideration of a transition towards accelerator-based devices.

DOI

10.21608/ajnsa.2020.116231

Keywords

electron beam, X-ray, Cobalt-60, alternative technologies, medical sterilization

Volume

53

Article Issue

4

Related Issue

17672

Issue Date

2020-10-01

Receive Date

2020-08-27

Publish Date

2020-10-01

Page Start

102

Page End

111

Print ISSN

1110-0451

Online ISSN

2090-4258

Article File

AJNSA_Volume 53_Issue 4_Pages 102-111.pdf

PDF . 592.3kB

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https://ajnsa.journals.ekb.eg/article_116231.html

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https://ajnsa.journals.ekb.eg/service?article_code=116231

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Original Article

Type Code

455

Publication Type

Journal

Publication Title

Arab Journal of Nuclear Sciences and Applications

Publication Link

https://ajnsa.journals.ekb.eg/

MainTitle

Replacement of Cobalt in Medical Device Sterilization: Current Trends, Opportunities and Barriers to Adoption of X-ray and E-Beam Within the Medical Device Sterilization Market

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Article

Created At

22 Jan 2023