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81561

Comparison of intensity modulated and 3- dimensional conformal ‎radiotherapy for prostate cancer using ‎6-MV and 15-MV photon ‎energies

Article

Last updated: 22 Jan 2023

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Abstract

Prostate cancer is one of the commonest cancers in men. The purpose of this work was to compare ‎between ‎intensity-modulated radiotherapy (IMRT) versus three-dimensional conformal radiotherapy ‎‎(3D-CRT) planning in patients with prostate cancer using 6-MV and 15-MV photon energies. Twenty ‎patients with localized prostate cancer were planned on Xio treatment planning system. Four treatment ‎plans were generated for each patient. IMRT whether 6 or 15 MV beam was slightly better in terms of ‎target coverage but not significant (p>0.05) in comparison to 3D-CRT in both beam energies. IMRT ‎was better than 3D-CRT in terms of organs at risk (OARs) sparing and conformity index (CI) in both 6 ‎and 15-MV whereas 3D-CRT in both 6 and 15-MV yielded better homogeneity index (HI) compared ‎to IMRT 6 and 15-MV. The number of monitor units (MU) increased in IMRT compared to 3D-CRT. ‎Also,‎‏ ‏MU increased in low energy compared to high energy whether in 3D-CRT or IMRT (p<0.05). ‎When IMRT 6-MV and IMRT 15-MV were compared, no significant difference was found in terms of ‎target coverage and OARs except the rectum was better in IMRT 6-MV compared to IMRT 15-MV. ‎IMRT 6-MV technique should be prioritized when user has options for treatment and then 3D-CRT as ‎a second line when the former is not available. The choice of the energies (6 and 15MV) used with ‎‎3D-CRT depend largely on patient's body geometry while the use of high energy IMRT 15-MV is not ‎recommended.‎

DOI

10.21608/ajnsa.2020.19402.1296

Keywords

Intensity modulated radiotherapy, 3D-conformal radiotherapy, high energy, prostate cancer ‎

Authors

First Name

Jamal

Last Name

AL-Shareef

MiddleName

-

Affiliation

Medical Biophysics, Sana&amp;#039;a University, Sana&amp;#039;a, Yemen

Email

jamal777207713@gmail.com

City

-

Orcid

0000000216932406

First Name

Ehab

Last Name

Attalla

MiddleName

-

Affiliation

Department of Radiotherapy and Nuclear Medicine, National Cancer Institute, Cairo University, &lrm;Cairo, Egypt

Email

attalla.ehab@gmail.com

City

-

Orcid

-

First Name

magdy

Last Name

Khalil

MiddleName

-

Affiliation

Physics Department, Faculty of Science, Helwan University, Cairo, Egypt

Email

magdy_khalil@hotmail.com

City

-

Orcid

-

First Name

Ahmed M

Last Name

Abdelaal &lrm;

MiddleName

-

Affiliation

&lrm; Radiotherapy Department, Nasser Institute, Cairo, Egyp

Email

mosa_science2010@yahoo.com

City

-

Orcid

-

Volume

53

Article Issue

2

Related Issue

11989

Issue Date

2020-04-01

Receive Date

2019-11-11

Publish Date

2020-04-01

Page Start

189

Page End

200

Print ISSN

1110-0451

Online ISSN

2090-4258

Link

https://ajnsa.journals.ekb.eg/article_81561.html

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https://ajnsa.journals.ekb.eg/service?article_code=81561

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Original Article

Type Code

455

Publication Type

Journal

Publication Title

Arab Journal of Nuclear Sciences and Applications

Publication Link

https://ajnsa.journals.ekb.eg/

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Article

Created At

22 Jan 2023