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Prostate cancer is one of the commonest cancers in men. The purpose of this work was to compare between intensity-modulated radiotherapy (IMRT) versus three-dimensional conformal radiotherapy (3D-CRT) planning in patients with prostate cancer using 6-MV and 15-MV photon energies. Twenty patients with localized prostate cancer were planned on Xio treatment planning system. Four treatment plans were generated for each patient. IMRT whether 6 or 15 MV beam was slightly better in terms of target coverage but not significant (p>0.05) in comparison to 3D-CRT in both beam energies. IMRT was better than 3D-CRT in terms of organs at risk (OARs) sparing and conformity index (CI) in both 6 and 15-MV whereas 3D-CRT in both 6 and 15-MV yielded better homogeneity index (HI) compared to IMRT 6 and 15-MV. The number of monitor units (MU) increased in IMRT compared to 3D-CRT. Also, MU increased in low energy compared to high energy whether in 3D-CRT or IMRT (p<0.05). When IMRT 6-MV and IMRT 15-MV were compared, no significant difference was found in terms of target coverage and OARs except the rectum was better in IMRT 6-MV compared to IMRT 15-MV. IMRT 6-MV technique should be prioritized when user has options for treatment and then 3D-CRT as a second line when the former is not available. The choice of the energies (6 and 15MV) used with 3D-CRT depend largely on patient's body geometry while the use of high energy IMRT 15-MV is not recommended.
DOI
10.21608/ajnsa.2020.19402.1296
Keywords
Intensity modulated radiotherapy, 3D-conformal radiotherapy, high energy, prostate cancer
Authors
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Medical Biophysics, Sana&#039;a University, Sana&#039;a, Yemen
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jamal777207713@gmail.com
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Department of Radiotherapy and Nuclear Medicine, National Cancer Institute, Cairo University, ‎Cairo, Egypt
Email
attalla.ehab@gmail.com
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-MiddleName
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Physics Department, Faculty of Science, Helwan University, Cairo, Egypt
Email
magdy_khalil@hotmail.com
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‎ Radiotherapy Department, Nasser Institute, Cairo, Egyp
Email
mosa_science2010@yahoo.com
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https://ajnsa.journals.ekb.eg/article_81561.html
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https://ajnsa.journals.ekb.eg/service?article_code=81561
Publication Title
Arab Journal of Nuclear Sciences and Applications
Publication Link
https://ajnsa.journals.ekb.eg/
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