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65824

Peripheral Photon Doses from Different Techniques Delivered in Prostate Radiotherapy: Experimental Measurements and TPS Calculations.

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Last updated: 22 Jan 2023

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Abstract

Advanced techniques and modalities in delivering radiotherapy improved the ability of delivering higher tumor doses while minimizing dose to the critical organs. The aim of this work is to determine experimentally out-of-field doses associated with these modern radiotherapy techniques for actual clinical case of prostate carcinoma and intercompare it with the treatment planning system (TPS) calculations. Three prostate treatment plans of the intensity-modulated radiation therapy (IMRT), RapidArc, and the Three-Dimensional Conformal Radiotherapy (3D-CRT) techniques were delivered to an anthropomorphic phantom using 6 MV photons beams produced from a UNIQUE linear accelerator. The out-of-field surface doses at various distances from the isocenter and peripheral doses to organs at risk (OARs) were measured using the thermoluminescent detectors (TLD-700) then compared to the calculated doses from the used commercial Eclipse TPS version 11. The two implemented algorithms in the Eclipse TPS (analytical anisotropic algorithm, AAA and the Acuros XB algorithm, AXB) underestimated the surface out-of-field doses by a maximum average deviation of 49% till the distance of 15 cm from the isocenter reported to the 3D-CRT technique. IMRT and RA techniques were more precise than 3D-CRT in tumor coverage and sparing of OARs but resulted in larger peripheral photon doses. RA technique has the advantage of less treatment time than IMRT technique and also produce less peripheral photon doses because it uses fewer monitor units. Our results show that although AXB algorithm is significantly faster in dose calculations than AAA algorithm especially in modern techniques, but less accurate in estimating the out-of-field doses.

DOI

10.21608/ajnsa.2019.13839.1222

Keywords

Out-of-field doses, TLD-700, AAA algorithm, AXB algorithm, Prostate Cancer

Authors

First Name

Hala

Last Name

Azab

MiddleName

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Affiliation

Ionizing Radiation Metrology Lab., National Institute of Standards, Giza, Egypt.

Email

halasoliman4@yahoo.com

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Orcid

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First Name

Ranya

Last Name

Moussa

MiddleName

-

Affiliation

Radiation Therapy Department, Faculty of Medicine, Cairo University,Cairo, Egypt.

Email

ranya_moussa@yahoo.com

City

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Orcid

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First Name

Maha

Last Name

Kamaleldin

MiddleName

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Affiliation

Radiation Therapy Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Email

dr.mahakamaleldin@gmail.com

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Orcid

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Volume

53

Article Issue

1

Related Issue

10143

Issue Date

2020-01-01

Receive Date

2019-06-19

Publish Date

2020-01-01

Page Start

67

Page End

75

Print ISSN

1110-0451

Online ISSN

2090-4258

Link

https://ajnsa.journals.ekb.eg/article_65824.html

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https://ajnsa.journals.ekb.eg/service?article_code=65824

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7

Type

Original Article

Type Code

455

Publication Type

Journal

Publication Title

Arab Journal of Nuclear Sciences and Applications

Publication Link

https://ajnsa.journals.ekb.eg/

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Article

Created At

22 Jan 2023