Radon concentrations have been measured using Sealed Can Technique with CR-39 detector for twenty collected samples from Hamash gold mine area, South Eastern Desert of Egypt. This area is one of the most important areas of gold-bearing granites in Arabian Nubian Shield and being used as a gold mine. Radon comes into the air from the natural decay of radium deposits in the rocks depending on the geographical and the geological features of the study region. The average values of radon concentrations, exhalation rates, annual effective doses, and working levels are found to be equal to 27.18 ± 0.13 kBqm-3, 3.27 ± 0.03 Bqm-2h-1, 686.27 ± 5.15 mSvy-1 and 2.94 ± 0.02 respectively. The results indicate that the radon concentrations of all samples are higher than the recommended world limit given by ICRP and IAEA. The present study can be used to assess any changes in the radioactive background and any harmful radiation effect on the human in this area.