The available experimental data for 7Li(p,p)7Li elastic scattering have been investigated using both optical potential as well as single folding optical potential in which the real part of potential is derived on the basis of single folding model. Approximated optical potential parameters have been obtained for real part using DFPOT code. The real part was normalized and imaginary part was optimized at all range of energies. The calculated normalization factor NR was 0.8. The agreement between experimental data and theoretical calculations has been achieved at the different concerned energies using ECISS88 program. The calculation of astrophysical S-factor for 7Li(p,γ)8Be radiative capture reaction has been performed using potential model. Different sets of optical potential parameters have been used during analysis. It has been found that different potential parameters play a crucial role and has a significant effect on the calculated S-factor. It has been shown that optical parameters have the greatest effect on astrophysical S-factor through our calculation.