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4805

Effect of feeding some herbs on serum liver enzymes, total cholesterol, triglycerides and lipoproteins in hypercholesterolemic rats

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Last updated: 22 Jan 2023

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Abstract

The present work was carried out to study effects of feeding hypercholesterolemic rats with 3 herbs viz.: ginger, psyllium and coriander herbs, alone and in combination, mixed with the basal diet on serum liver enzymes, total cholesterol, triglycerides (TG) and lipoproteins. This study was conducted on 50 adult male rats divided into 10 equal groups. One group was fed on the basal diet only (control -ve). The other group was fed on the basal diet mixed with 1.5% cholesterol (control +ve). The remaining groups were fed on the basal +1.5% cholesterol + the studied herbs at 5 % and 10 %. After 6 weeks feeding on the experimental diets, al! rats were weighed for calculation of body weight gain and food efficiency ratio. Blood samples were collected for estimation of liver enzymes, cholesterol, TG and lipoproteins in the serum. Histopathology of liver was also carried out. The obtained results revealed that feeding hypercholesterolemic rats on diets mixed with each of these herbs, alone or in combination at 5% and 10 %, improves the liver function as it lowers the elevated serum. AST and ALT enzymes. It induces also hypocholesterolemic and hypolipidmic effects. Moreover, it alleviates the histopathological changes in the liver induced by cholesterol feeding. However, it reduces daily food intake, body weight gain, food efficiency ratio and liver weight in the tested rats. It was concluded that feeding combined formula of ginger, psyllium, coriander each or combined at 5% and 10 % for 6 weeks may be useful in the management of cases suffering from hypercholesterolemia associated with elevated liver enzymes.

DOI

10.21608/ejnh.2006.4805

Keywords

Ginger, Psyllium, Coriander, liver enzymes, histopathology, rat

Authors

First Name

Dalia

Last Name

Hafez

MiddleName

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Affiliation

Home Economics Department, Faculty of Education, Suez Canal

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Volume

1

Article Issue

1

Related Issue

804

Issue Date

2006-01-01

Receive Date

2018-01-02

Publish Date

2006-01-01

Page Start

1

Page End

19

Print ISSN

1687-7950

Online ISSN

2535-1559

Link

https://ejnh.journals.ekb.eg/article_4805.html

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https://ejnh.journals.ekb.eg/service?article_code=4805

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8

Type

Original Article

Type Code

443

Publication Type

Journal

Publication Title

Egyptian Journal of Nutrition and Health

Publication Link

https://ejnh.journals.ekb.eg/

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Article

Created At

22 Jan 2023