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277931

Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Impact of nutritional science on human health

Abstract

Infantile colic is one of the most distressing early-life manifestations. Sudden episodes of inconsolable crying without a clear reason or treatment plan might cause parents to try incorrect methods, which can injure the infant. Many treatment strategies were developed to solve this dilemma; the effectiveness of each is still doubtful. Objective: To compare the effect of probiotics as a recent therapy in the management of infant colic and herbal remedies as one of the most commonly used strategies. By searching national and international databases, 24 randomized clinical trials RCT studies were included (19 examining the effect of probiotics, 5 for herbal remedies). Results: The most researched probiotic, Lactobacillus reuteri, exhibits statistically significant improvement and a decrease in the daily average crying time >=50% on days 7, 14, and 21. On day 7, RR (95% CI): 4.3 (2.3-8.7), P value 0.026; on day 14, RR (95% CI): 4.3 (2.3-8.7), P value< .001. A phase III, double-blind, randomized placebo-controlled trial found that the lactobacillus reuteri group cried or fussed for 49 minutes longer than the placebo group, (95% confidence interval 8 to 90 minutes, P=0.02). Fennel emulsion was the most studied in the herbal group with significant improvement to the placebo group (p< 0.01) absolute risk reduction (ARR):41% (95% CI 25 to 57). Conclusions: None of the therapies shows dramatic improvement, and probiotic supplementation's long-term effects are still a concern. More research is needed including local herbal remedies of our community.

DOI

10.21608/bnni.2022.277931

Keywords

(herbal for infant colic), (probiotic for infant colic)

Authors

First Name

Gihan

Last Name

Ahmad

MiddleName

F

Affiliation

National Nutrition Institute

Email

-

City

Cairo

Orcid

-

First Name

Hanna

Last Name

Abdel Wahab

MiddleName

M

Affiliation

National Nutrition Institute

Email

-

City

Cairo

Orcid

-

First Name

Eman

Last Name

Elkronfoly

MiddleName

I

Affiliation

Qaha specialized hospital, ministry of health

Email

-

City

Banha

Orcid

-

First Name

Fatma

Last Name

Rabie

MiddleName

EO

Affiliation

Manshyat Elbakry general hospital, ministry of health.

Email

-

City

Cairo

Orcid

-

First Name

Samah

Last Name

Mohamed

MiddleName

A

Affiliation

Berket El-Sabae hospital, ministry of health

Email

-

City

kwesna

Orcid

-

First Name

Sara

Last Name

Mostafa

MiddleName

MN

Affiliation

Alexandria police hospital

Email

-

City

Alexandria

Orcid

-

First Name

Shireen

Last Name

Sharaf

MiddleName

S

Affiliation

El-menshawy general hospital, ministry of health

Email

-

City

Cairo

Orcid

-

Volume

60

Article Issue

2

Related Issue

36271

Issue Date

2022-12-01

Receive Date

2023-01-01

Publish Date

2022-12-01

Page Start

180

Page End

211

Print ISSN

1110-0974

Online ISSN

2537-0987

Article File

BNNI_Volume 60_Issue 2_Pages 180-211.pdf

PDF . 616.6kB

Link

https://bnni.journals.ekb.eg/article_277931.html

Detail API

https://bnni.journals.ekb.eg/service?article_code=277931

Order

277,931

Type

Original Article

Type Code

442

Publication Type

Journal

Publication Title

Bulletin of the National Nutrition Institute of the Arab Republic of Egypt

Publication Link

https://bnni.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023