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162860

Protective Effect of the Red Quinoa Seeds versus Oxidative Stress Induced by Alloxan and Carbon Tetrachloride in Experimental Rats

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Nutritional quality of novel foods

Abstract

ABSTRACT
The Red Quinoa seeds (RQ seeds) shows a higher number of total phenolic and flavonoids content. Therefore, the protective effect of the RQ seeds versus oxidative stress induced by Alloxan and carbon tetrachloride (CCl4) may treatment in rats. Fifty-six healthy male albino rats were randomly divided into three main groups. The first group of healthyrats (8 rats) was negative control and fed on commercial diet. The second group (24 rats) received CCl4 injections subcutaneously (for two weeks); while, the third group (24 rats) were fasted for 24 hours, injected with one dose prepared Alloxan by intraperitoneal injection to induce oxidative Stress. Then both main 2 groups were divided into 3 subgroups (8rats /each) and treated by different concentrations of RQ seedsas for 6 weeks. The rats were weighed weekly and at the end of the experimental, the animals were fasted overnight, anesthetized; sacrificed and weighted the organs excise" liver, kidney and Pancreas". Results showed that stress groups (Alloxan and CCl4) were significantly increased risk for oxidative stress. However, the results indicated that a diet fortified at 5g and 10g RQ seeds improves weight gain, increased antioxidant enzymes (SOD, CAT and GPx), reduces liver enzymes, kidney function, lipid profiles, serum glucose and reduces the risk of organ functions (liver, kidney and pancreas), related to oxidative stress, when compared to stress groups. More specifically, a diet with 10g RQ seeds reduced the adverse effect of oxidative stress.

DOI

10.21608/bnni.2020.162860

Keywords

Red quinoa seeds, Oxidative Stress, CCl4, alloxan

Authors

First Name

Walaa

Last Name

Aniess

MiddleName

I

Affiliation

Home Economic Dept., Faculty of Specific Education, Ain Shams University, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Safaa

Last Name

Gohari

MiddleName

T

Affiliation

Home Economic Dept., Faculty of Specific Education, Ain Shams University, Cairo, Egypt

Email

drsafaa@sedu.asu.edu.eg

City

Cairo

Orcid

-

First Name

Amr

Last Name

Goma

MiddleName

A

Affiliation

GC-MS lab, National Nutrition Institute, Cairo, Egypt

Email

-

City

Cairo

Orcid

-

First Name

Wafaa

Last Name

Ahmad

MiddleName

A

Affiliation

Home Economic Dept., Faculty of Specific Education, Ain Shams University,Cairo, Egypt

Email

wafaa01154@gmail.com

City

Cairo

Orcid

-

Volume

55

Article Issue

1

Related Issue

23814

Issue Date

2020-06-01

Receive Date

2020-04-10

Publish Date

2020-06-01

Page Start

1

Page End

38

Print ISSN

1110-0974

Online ISSN

2537-0987

Article File

BNNI_Volume 55_Issue 1_Pages 1-38.pdf

PDF . 2.6MB

Link

https://bnni.journals.ekb.eg/article_162860.html

Detail API

https://bnni.journals.ekb.eg/service?article_code=162860

Order

1

Type

Original Article

Type Code

442

Publication Type

Journal

Publication Title

Bulletin of the National Nutrition Institute of the Arab Republic of Egypt

Publication Link

https://bnni.journals.ekb.eg/

MainTitle

Protective Effect of the Red Quinoa Seeds versus Oxidative Stress Induced by Alloxan and Carbon Tetrachloride in Experimental Rats

Details

Type

Article

Created At

22 Jan 2023