Objectives: Determinations of sex utilizing skeletal remains still displays a difficult issue to forensic specialists, particularly when body fragments are only found in mass disaster, car or plane accidents, fires, and even in the investigations of crimes. Sinus radiography is one these methods that was utilized for determining the sex of a person. Consequently, Consequently the aim of the present study was to evaluate the reliability of the morphometric dimensions of maxillary sinus in determination of sex and age via computed tomography (CT) scan images as paranasal sinuses still undamaged whether the skull and other bones are seriously blemished or not. Methodology: The present work involves 30 adult cases (15 males and 15 females) who were referred to radiodiagnosis department of Beni-sueif university hospital. The determination of the length, height and width of right and left maxillary sinuses were performed using CT scan and statistical analyzing was performed. Results: there was a statistically significant (P < 0.05) difference in the width of the left maxillary sinus between females and males while the other dimensions of the left and right maxillary sinuses showed insignificance difference (P > 0.05). Conclusion: Dimensions of maxillary sinuses alone cannot be used as an accurate diagnostic parameter for sex determination.