Identification of human skeletal remains is an important step during mass disasters, from decayed and damaged dead bodies. In forensic investigations and in medicolegal cases, identification of sex is an important aspect, followed by age determination. Skeletal components most often investigated for gender determination are pelvis and skull with mandible being a practical element to analyse sexual dimorphism in fragmented bones. Mandible is the largest, strongest and movable part of skull. The present study was designed to compare between mandibular ramus measurements and mental foramen relations on both sides to determine sex through digital panoramic radiography. The present study included 150 adult patients 75 were males and 75 were females. The present study revealed that, there was no significant difference between right and left sides regarding all measured mandibular and mental foramen parameters in both males and females. There was significant statistical increase in the mean values of all measured mandibular and mental foramen parameters in males as compared with females except right and left Min.R.Br . While there was no significant statistical difference between males and females. The mean values of right and left Condylar.R.Ht and SM-IB were the most correct predictors of both genders.