Anthropometry is the branch of science dealing with body measurements, its roots dating back since ancient times. It finds its way to many disciplines including medicine, industry, and forensic sciences. Hand anthropometry is an important player in medical diagnosis, manual tools design, and personal identification. Objective: Developing a new technique for Photo-Anthropometry based on hand photos, and to apply this technique on a sample of adult Egyptians. Methodology: Development of a software based on a new technique for Photo-Anthropometry, and testing the software for twenty one hand measurements carried on photos of the right hand of 113 adult Egyptians volunteers (58 males, 55 females) from three different geographical areas (Kafr El-Sheikh, Giza, and Fayoum). Results: The new method is simple, easy, and accurate, as the photo is calibrated to overcome the magnification problem common in photo-anthropometry. The accuracy of the measurements was 0.397%. The new system have a unique feature as it can locate calculated points based on simple landmarks. However the proposed method apply only in co-planner measurements. The mean, standard deviation, and percentiles were calculated for the twenty one hand measurements. In addition, two predictive polynomial equations calculating percentiles of hand length and hand width were developed, as well as sex differences were reported. Conclusion: The new developed method is accurate and easy to use which enable absolute measurements on hand photos.