Background: The dilemma for stature estimation from the skeleton is of great medico-legal importance. Stature is one of the fundamental features that may assist in the recognition of an individual in situations of mass disasters or in cases of absent main body parts. Aim: to predict stature from hand measurements, (length and breadth) in four different population groups (Egyptians, Saudi Arabians, Indians, and Filipinos) and to establish formulae for stature estimation for each group. Methods: Eight hundred right- hand predominant subjects (400 males and 400 females) belonging to four different population groups (100 males and 100 females for each group) aged 17-58 years have participated in the current work. Each one has been investigated for measurements of stature, hand length, and the hand breadth. Obtained data were statistically analyzed using the SPSS Statistics for Windows version 25. Results: Linear regression equations reveal a fairly accepted rate of accuracy with a standard error of estimate (1.92 - 4.77) in respect to hand length of males and (3.31 - 4.24) for females. For hand breadth, the standard error of estimate was (2.43 - 4.73) for males and (3.01 - 4.51) for females. Conclusion: this study can be useful to predict stature from a dismembered hand when it is subjected for medico-legal examination that may highlight the expected medico-legal implications on the practical background.