Toxoplasma gondii, included in the Phylum Apicomplexa, is a tissue parasite in the intermediate host and an intestinal parasite in the feline definitive host and needs no vector. In the tissues, it replicates asexually by endodyogeny, and endopolygeny; and asexually and sexually by schizogony and gametogony in cat ileum giving rise to infective oocysts. In vitro culture in cell lines provide a suitable model for studying proliferation of the parasite. Retrograde examination of permanent preparations demonstrating morphological forms of multiplying Toxoplasma in an in vitro culture cell line, revealed what may be considered gametogonic stages.