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258087

Is there is a link between oral microbiome and chronic liver diseases

Article

Last updated: 03 Jan 2025

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Abstract

Background: The oral cavity is a large reservoir of bacteria of more than 700 species or phylotypes and is strongly relevant to host health and disease. The oral microbiota plays an important role for keeping our health by creating a protective layer in the mouth which stops colonization by pathogens. If the microbial composition is disturbed, the oral microbiota may encourage a state of disease in the oral or extra-oral tissues such as the liver. Evidence suggests that a link exists between dysbiotic oral microenvironment and liver disease through oral-liver-gut axis. Dysbiosis, defined as a pathological change in the microbiome, has a variable effect on the compensated and decompensated liver cirrhosis. Previous research revealed that, people with cirrhosis have changes in the gut and salivary microbiota, which can lead to gum disease and a higher risk of corrhotic complications. Moreover, studies have institute that, people with cirrhosis have increased levels of inflammation throughout the body, which is associated with hepatic encephalopathy. The aim of this review is to provide a current overview of alterations in the oral microbiota associated with chronic liver diseases.
 

DOI

10.21608/mjvh.2022.258087

Keywords

Oral microbiome, oral-liver-gut axis, Chronic liver diseases

Authors

First Name

Eman

Last Name

Mousa

MiddleName

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Affiliation

Faculty of Dentistry, Mansoura University, Mansoura, Egypt

Email

eman.nasser.mousa@gmail.com

City

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Orcid

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First Name

Rashd

Last Name

Hassan

MiddleName

-

Affiliation

Tropical Medicine department. Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Email

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City

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Orcid

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Volume

6.3

Article Issue

3

Related Issue

36449

Issue Date

2022-08-01

Receive Date

2022-08-20

Publish Date

2022-08-31

Page Start

19

Page End

21

Print ISSN

2314-8748

Online ISSN

2314-8756

Link

https://mjvh.journals.ekb.eg/article_258087.html

Detail API

https://mjvh.journals.ekb.eg/service?article_code=258087

Order

3

Type

Original article

Type Code

477

Publication Type

Journal

Publication Title

Medical Journal of Viral Hepatitis

Publication Link

https://mjvh.journals.ekb.eg/

MainTitle

Is there is a link between oral microbiome and chronic liver diseases

Details

Type

Article

Created At

22 Jan 2023