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Prevalence of low androgen levels among middle and old age men attending Outpatient Clinics

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Last updated: 22 Jan 2023

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Abstract

Introduction: Tiredness is a common symptom of hypogonadism, which can be profound, but there are many medical practitioners who do not include the assessment of testosterone levels in the clinical workup of this symptom. Although male hypogonadism is an established clinical condition, which can be treated, many men experiencing it are undiagnosed.
ِAim:The aim was to assess the prevalence of low androgen level among middle and old age men in a cohort of patients attending Kasr Elaini hospital outpatient clinics.
Patients and Methods: A total of 265 male patients older than 40 years attending the outpatient clinics in different specialty were included. All included men were subjected to full history taking and complete general and local examinations. All participants were interviewed personally face to face using Arabic generic version of full aging male scale (AMS) questionnaire. Venous blood samples were withdrawn between 8 and 10 a.m. after a 12-h overnight fast for measurements of total and free testosterone levels.
Results: The mean total testosterone level was 4.0 ± 2.6 ng/ml, ranging from 0.4 to 16.4 ng/ml. The mean free testosterone level was 6.9 ± 2.4 pg/ml, with range between 1.4 and 18.5 pg/ml. Low androgen level was founded in 19.2% of the participants based on total testosterone and in 36.2% when adding the participants with low free testosterone levels. AMS score showed statistically significant difference between age groups (P<0.001). Age is negatively correlated with total and free testosterone levels (r=-0.226 and -0.242, respectively), but the correlation is weak. Total testosterone level shows strong positive correlation with free testosterone level and weak negative correlation with AMS score (r=0.732 and -0.240, respectively).
Conclusion: The prevalence of hypogonadism among middle and old age males seeking medical consultation in different specialties may be high.

DOI

10.21608/ha.2018.4072.1028

Keywords

Hypogonadism, low androgen, middle and old age, testosterone

Authors

First Name

Taha

Last Name

Abdelnaser

MiddleName

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Affiliation

Departments of Andrology, Faculty of Medicine, Cairo University, Cairo

Email

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City

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Orcid

-

First Name

Dina

Last Name

El Gayar

MiddleName

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Affiliation

Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Cairo

Email

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City

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Orcid

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First Name

Islam

Last Name

Fathy

MiddleName

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Affiliation

Lecturer of Andrology, Andrology Dept., Faculty of Medicine, Cairo University.

Email

islamandrology@yahoo.com

City

-

Orcid

0000-0001-6469-5858

First Name

Ramy

Last Name

Taher

MiddleName

-

Affiliation

Ministry of Health Hospitals, Egypt, Cairo

Email

dr_ramytaher@hotmail.com

City

-

Orcid

-

Volume

8

Article Issue

2

Related Issue

4342

Issue Date

2018-06-01

Receive Date

2018-12-30

Publish Date

2018-06-01

Page Start

53

Page End

59

Print ISSN

2090-6048

Online ISSN

2090-6056

Link

https://ha.journals.ekb.eg/article_23100.html

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https://ha.journals.ekb.eg/service?article_code=23100

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4

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Original Article

Type Code

367

Publication Type

Journal

Publication Title

Human Andrology

Publication Link

https://ha.journals.ekb.eg/

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Article

Created At

22 Jan 2023