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28776

Role of immunomodulation with lymphocyte immunization therapy (LIT) in a couple with 15 unexplained repeated miscarriages

Article

Last updated: 03 Jan 2025

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Abstract

The problem of repeated miscarriages affects 0.5-2% of population. The current case is with history of 15 unexplained miscarriages following both, spontaneous conceptions and after IVF. All the routine investigations were normal. She had been treated with all the established methods of treatment without success. She was diagnosed with allo-immune cause of miscarriages and was given Lymphocyte Immunization Therapy (LIT). Her pregnancy successfully went till term. There were no side effects of the LIT to the mother or the baby. A case with higher number of repeated miscarriages is more likely to be due to allo-immune rejection of pregnancy. Immunomodulation with active immunotherapy in the form of LIT is still an effective therapy in properly selected cases.

DOI

10.21608/EBWHJ.2019.28644

Keywords

Allo-immunity, Immunotherapy, lymphocyte immunization therapy (LIT), unexplained repeated miscarriages, unexplained recurrent miscarriages

Authors

First Name

Raut

Last Name

Mugdha

MiddleName

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Affiliation

Partners, Dr. Raut's Immunotherapy Centre for Prevention of Repeated Miscarriages (ICPRM), Mumbai

Email

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City

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Orcid

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First Name

Mohan

Last Name

Raut

MiddleName

-

Affiliation

Immunotherapy Centre for Prevention of Repeated Miscarriages (ICPRM), Mumbai, India

Email

mohan@drraut.com

City

-

Orcid

-

Volume

9

Article Issue

1

Related Issue

5102

Issue Date

2019-02-01

Receive Date

2018-10-08

Publish Date

2019-02-01

Page Start

390

Page End

393

Print ISSN

2090-7265

Online ISSN

2090-7257

Link

https://ebwhj.journals.ekb.eg/article_28776.html

Detail API

https://ebwhj.journals.ekb.eg/service?article_code=28776

Order

10

Type

Case Report

Type Code

397

Publication Type

Journal

Publication Title

Evidence Based Women's Health Journal

Publication Link

https://ebwhj.journals.ekb.eg/

MainTitle

Role of immunomodulation with lymphocyte immunization therapy (LIT) in a couple with 15 unexplained repeated miscarriages

Details

Type

Article

Created At

22 Jan 2023