Background: Knee OA is a major publ ic heal th problem among elderly. I t is a debi l i tating condi tion associated
wi th increased morbidi ty and disabi l i ty . Thus, the development of therapeutic interventions could enhance the
qual i ty of l i fe for the elderly
Aim: To evaluate the cl inical effi cacy of platelets rich plasma int ra articular injections in t reatment of Knee
Osteoarthri tis among Elderly.
Methods: one arm cl inical t rial on 44 elderly par ticipants al l of them received a single session of intraarticular
PRP injection, they were subjected to physical function and mobi l i ty assessment using Western Ontario and
McMaster Universi ties Ar thri tis Index (WOMAC) questionnai re and pain assessment by the numeric pain rating
scale (NRS-11) at 6 and 12 months post injection.
Results: study reported a statistical ly signi ficant improvement in al l functional WOMAC assessment scores and
NRS after 6 months and 12 months post injection fol low up wi th the tendency for gradual decl ine of cl inical
improvement ti l l the end of fol low up after 1 y ear.
Conclusions: Intraar ticular PRP injections are safe, effective and rel iable t reatment option providing functional
improvement and pain cont rol for elderly patients wi th knee OA