The aim of this research was mainly to study the knowledge of rural women about the harmful effects of some manufactured food on children's health. Data were collected throughout personal interviews and questionnaires for a sample of 293 women using the formula of Krejcie and Morgan (1970). The selected villages were Monshat El-Masri, Sidi Salem region, El-Hodod Village, Kafr El-Sheikh Region, and El-Bashir, Riyadh region. Data were statistically analyzed, and iteration, percentage, mean, and standard deviation have been taken into account to get the following findings (1) about 67% of women have an average knowledge of the harmful effects of some manufactured food on children's health. (2) The most frequently used source of information was the pediatrician and the rest of the sources were traditional, such as personal experience, husband, and educated children in the family. (3) Fifteen children diseases, such as stomach pain, diarrhea, vomiting, fever, and allergy are largely affected children's health. Other diseases were found to be slightly effective.