The present work was carried out to study the effect of some saftey compounds, i.e. plant guard (Trichoderma harzianum), humic acid and compost tea and resistance inducers (salicylic acid and benzothiadiazole) besides fungicide (Vitavax-T)) on controlling soil borne diseases such as root rot and wilt of pea plants (cv. Master-B). Data comprised growth, yield and quality parameters under greenhouse and open field conditions during 2012 and 2013 growing seasons. All safe compounds and inducers were evaluated to control Fusarium solani, Fusarium moniliform, Fusarium oxysporum and Macrophomina phaseolina, the causal agents of pea root rot and wilt diseases compared to fungicide. Most treatments significantly protected pea plants from pre and post-emergence damping off, increased pea growth and yield components compared to control plants. Under open field conditions, pea plants were infected naturally with F. oxysporum f.sp. pisi, wilt % was significantly reduced by all treatments compared to untreated plants (control). As a result of treatments, vegetative growth parameters (plant height, No. of leaves ∕plant, plant fresh and dry weight), chlorophyll content, yield parameters (green pod yield, total dry seed yield, pod length and weight of 100 seeds) and catalase antioxidant enzyme of pea plants were increased significantly compared to untreated plants. These results provide alternative and safe compounds to control pea wilt diseases and consequently, save the fungicide cost , reduce environmental pollution as well as improving plant growth and total yield of pea plants.