The study focuses on effect of the complementation between the plant growth promoting rhizobacteria (PGPR) such as Streptomyces erythrogriseus 2, Bacillus cereus 54-1, and Spirulina platinsis on the growth and the quantity of oil sesame under different rates of familiar manure 0, 2, 4 ton/fed. Results indicated inoculation mixture of Bacillus cereus54-1, Streptonyces erythrogreiseus sp 2 and Spirulina platinsis had the greatest effect on dehydrogenase activity (254.0 μg TPF/g dry soil), while root colonization Bacillus cereus54-1, the uppermost values with 60 % colonization. The photosynthetic test was carried out where implementation of all microbes resulted in the highest chlorophyll a content with 2.03 mg/ g dry weight. Growth parameters was estimated, the treatment of bacteria Bacillus cereus54-1, Streptonyces erythrogreiseus sp 2 gave the highest values of Root length, Shoot height, number of branches and shoot dry weight were 22.1,22.2 cm/plant root length 153,156.2 cm/plant shoot height,4.5,4.5 number of branches and 50.3,49.4 gm./plant shoot dry weight. Bacillus cereus54-1, Streptonyces erythrogreiseus sp 2 gave the highest values of shoot height, number of pods weight of 1000 seed and seeds Kg/fed number being, 169.7,159.0 cm/plant, pods number /plant and 5.4,5.97 weight of 1000 seed/plant, and 5.8,5.67seed Kg/Fadden respectively. However, the highest values of N, P and K were, 17.29, 7.9 and 62.20 (mg.kg-1 soil) obtained under the treatment of bacterial Bacillus cereus54-1, respectively. The highest seed oil percent was observed in treatments Bacillus cereus 54-1 and Streptomyces erythrogreiseus sp 2 where the heights seed oil percent was 51,48 Kg/fed compared to the control.