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5450

The Value of Tc-99m MIBI Washout Rate in Detection of Ischemia compared with standard Myocardial Perfusion Imaging

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Last updated: 03 Jan 2025

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Abstract

Objective: we aimed to estimate the rate of MIBI washout of myocardium in patients with clinical ischemia as compared to the degree of reversibility between stress and rest studies.
Patients and methods: this prospective study included 50 patients [34 males (60%) & 16 females (40 %)] with mean age 55.3 ± 10.1 years. All patients underwent ECG-gated SPECT Tc-99m MIBI myocardial perfusion imaging. Two days protocol (rest/stress) was used, the rest study was performed at 90 min and delayed images at 4 hours post-injection. While in stress phase images were performed after 30 min. The polar map of perfusion images acquired at stress and rest images at 90 min to detect reversibility. Also, polar map of 90 min was compared with delayed perfusion images at 4 h to calculate washout rate.
Results: there was higher WR in the ischemic myocardial region of LAD (21.18±7.2) compared to the normal one (9.96±2.49), (p < 0.001). Also, in the region of RCA WR was 19.17±3.86 in ischemic wall versus 9.59±1.69 in normal walls (p<0.02) and (LCX) WR was 17.02 ± 2.6 in ischemic wall versus 9.63 ± 1.76 in normal walls (p<0.04). Additionally, the linear correlation of regional WR of each vascular territory was compared with the corresponding degree of reversibility with statistically significant for LAD (0.77), LCx (0.86) and RCA (0.64).
Conclusion: There is higher WR of MIBI in ischemic walls in all vascular territories with significant correlation with its degree of reversibility that may potentiate the results of stress study.

DOI

10.21608/egyjnm.2014.5450

Keywords

Tc-99m MIBI, CAD

Authors

First Name

Hosna

Last Name

Moustafa

MiddleName

-

Affiliation

Oncology and Nuclear Medicine Department, Kasr Al-Aini Hospital, Cairo University, Egypt.

Email

drhosna1947@gmail.com

City

-

Orcid

-

First Name

Mahasen

Last Name

Abo-gabal

MiddleName

-

Affiliation

Nuclear Medicine, NEMROCK Center, Faculty of Medicine, Cairo University, Cairo, Egypt.

Email

kodomojanai20@yahoo.com

City

-

Orcid

-

First Name

Omar

Last Name

M

MiddleName

-

Affiliation

NEMROCK Center, Cairo University, Egypt

Email

m.omarosman@yahoo.com

City

-

Orcid

0000-0002-0974-0481

First Name

Sherif

Last Name

El-maghrapy

MiddleName

-

Affiliation

Oncology and Nuclear Medicine Department, Kasr Al-Aini Hospital, Cairo University, Egypt.

Email

ry_maghraby@hotmail.com

City

-

Orcid

-

Volume

10

Article Issue

10

Related Issue

257

Issue Date

2014-06-01

Receive Date

2018-02-21

Publish Date

2014-06-01

Page Start

18

Page End

32

Print ISSN

1687-4994

Online ISSN

2536-9113

Article File

EGYJNM_Volume 10_Issue 10_Pages 18-32.pdf

PDF . 955.0kB

Link

https://egyjnm.journals.ekb.eg/article_5450.html

Detail API

https://egyjnm.journals.ekb.eg/service?article_code=5450

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Type

Original Paper, Cardiology

Type Code

381

Publication Type

Journal

Publication Title

Egyptian Journal Nuclear Medicine

Publication Link

https://egyjnm.journals.ekb.eg/

MainTitle

The Value of Tc-99m MIBI Washout Rate in Detection of Ischemia compared with standard Myocardial Perfusion Imaging

Details

Type

Article

Created At

22 Jan 2023