Introduction: Comparative Anatomy is the study of structural relationships and modifications in anatomy of structures in
different organisms. The current research was aimed at finding the gross, morphological and histological differences and
similarities in the testes of the Agama Lizard and Albino Rat.
Materials and Methods: Five adult, healthy Albino rats and Agama lizards were obtained for the study. The animals were
sacrificed and an incision was made to expose the testes which were removed and morphologically examined. Several
parameters were measured and the results analyzed.
Results: Gross assessment revealed that the testes were found in different locations in these species. Testicular length was
significantly (p < 0.05) increased in the left testicle of the Agama lizard. Testicular volume was significantly (p < 0.05) increased
in the right testes in Albino rats. The reverse was the case in the volume of testes in the Agama lizard.
Conclusion: Histomorphological assessment revealed that the germinal layer and seminiferous tubular area of the Agama
lizard was thicker than in the Albino rat. In the Agama lizard, there was reduced interstitial space and the basement membrane
of the seminiferous tubules closely abuted each other. The other structures were analogous and had similar anatomical and
histological appearance and performed the same physiological functions.