The present study was carried-out at Antoniadis Research Branch, Horticultural Research Institute, Agriculture Research Center (ARC), Alexandria, Egypt during two successive seasons of 2018 and 2019. The aim of this study was to evaluate the effects of irrigation water polluted with nickel on the growth of Lantana camara plants and the possibility of using citric acid spray treatments to overcome the effects of nickel pollution. Transplants of Lantana camara were planted individually in plastic pots (20 cm diameter) filled with 5 kg of sandy soil. The nickel polluted irrigation water treatments were 0, 100, 200 and 300 mg/l. The plants were monthly sprayed with citric acid at concentrations of 0, 250 and 500 mg/l. The results showed that for vegetative growth parameters there were non significant differences in the interaction between nickel concentrations and foliar spray with citric acid, while significant reduction was observed in all parameters after irrigation with nickel polluted water and significant increase in vegetative growth parameters were observed after 500 mg/l citric acid application. For total chlorophyll and carbohydrate content, the highest significant values were obtained in plants irrigated with tap water and sprayed with 250 mg/l citric acid while the highest significant level of nickel content in the leaves, stem and roots was obtained due treatment by 300 mg/l nickel without application of citric acid.