Objective: To quantify risk factors and feto-maternal outcomes in women
with singleton pregnancies complicated by placenta previa (PP).
Methods:Acase-control study comparing 157 women with singleton
pregnancies complicated by PP to a similar group without PP. The study
was conducted from January 2013 through March 2015 at Mansoura
University Hospitals, Egypt. Multiple logistic regression models were
used to control for confounders.
Results:Multivariate analysis indicated risk factors associated with PP
were: maternal age ≥ 30 years (OR=3.183, P= 0.004), parity ≥ 3 (OR=2.6,
P=0.016), prior caesarean deliveries ≥ 2 (OR=10.2, P=<0.001), previous
PP (OR=5.069, P=0.029) and previous uterine evacuation (OR=2.843,
p=0.023). Women with PP had increased risk of massive obstetrics
hemorrhage, emergency hysterectomy, admission to ICUand maternal
deaths. There was also increased risk to antepartum, intra-partum, and
postpartum blood transfusion, maternal sepsis, longer hospital stay. Also
infants of cases showed higher rates of perinatal mortality (4.5 vs. 0.6%;
P< 0.001), prematurity (23.4 vs. 1%, p < 0.001) and admission to NICU (14
vs. 1.9%, p=0.001).
Conclusions: Increasing maternal age, high parity, previous PP, previous
evacuation and prior caesarean delivery were independent risk factors
for PP. Adverse maternal and perinatal outcomes were also increased
significantly.