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257284

Prevalence of antithyroid antibodies in patients with unexplained infertility

Article

Last updated: 22 Jan 2023

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Abstract

Objective: To evaluate the relative prevalence of antithyroid antibodies in unexplained
infertility compared to other types of infertility.
Patients and methods: The study comprised of 96 subfertile couples and 80 parous
women attending outpatient clinic in Mansoura University Hospital. There were 30
patients had tubal causes, 16 patients had PCOS, 10 patients had endometriosis and 40 had
unexplained infertility. Antithyroid auto-antibodies (antithyrglobulin and antimicrosomal)
were estimated in the sera of all patients.
Results: There were no significant differences in the frequency of antimicrosomal
antibodies and antithyroglobulin in subfertile cases compared to the controls (25% and
22% versus 12% and 10%, P value 0.22 and 0.12, respectively). Subgroup analysis had
revealed significantly higher frequency of women with positive antimicrosomal and
antithyroglobulin antibodies in couples with unexplained infertility compared to fertile
controls.
Conclusion: A significantly higher proportion of thyroid auto-antibodies existed in
women with unexplained subfertility compared to the fertile women.

DOI

10.21608/egyfs.2012.257284

Keywords

Key words: Subfertility, thyroid antibodies, Unexplained infertility

Authors

First Name

Maged ragheb Elshamy,

Last Name

Hosam Z Elhafez

MiddleName

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Affiliation

Assistant professor of Obstetric and Gynecology, Obstetric and Gynecology Department, Mansoura University Hospital, Mansoura, EGYPT

Email

dr_maged66@yahoo.com

City

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Orcid

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Volume

16

Article Issue

1

Related Issue

36443

Issue Date

2012-01-01

Receive Date

2022-08-31

Publish Date

2012-01-01

Page Start

27

Page End

29

Print ISSN

1110-6352

Online ISSN

2536-9768

Article File

EGYFS_Volume 16_Issue 1_Pages 27-29.pdf

PDF . 963.5kB

Link

https://egyfs.journals.ekb.eg/article_257284.html

Detail API

https://egyfs.journals.ekb.eg/service?article_code=257284

Order

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Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

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Article

Created At

22 Jan 2023