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237722

Creatine Kinase as a diagnostic biochemical Marker in Placenta Accreta, Mansoura experience

Article

Last updated: 22 Jan 2023

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Abstract

Abstract
Background: placenta accreta is a life-threatening
pregnancy complication which usually accompanied with
placenta previa. It is important to make the diagnosis before
delivery therefore a preoperative planning will decrease
complications. The aim of this study was to evaluate the
possibility of using creatine kinase as a diagnostic and
prognostic marker in placenta accreta.
Methods: two groups were recruited; forty-five patients
diagnosed by ultrasound with placenta accreta as patient
group (group A) and another forty-five as controls (group < br />B). Maternal Creatine kinase level was measured using CKNAC FS* IFCC Technical bulletin and compared between
patients group and controls group.
Results: Our results indicated the presence of significant
difference between the patient group and the control group < br />regarding age (P-value= 0.01), gravidity (P-value= 0.01) and
parity (P-value= 0.006). While non-significant difference
regarding medical history (P-value= 0.59), surgical history
(P-value= 0.51), and D & C (P-value= 0.82). Our results
indicated no significant difference between both groups
regarding serum creatine kinase level (P-value= 0.29). We
have identified surgical complications and intraoperative
findings which occurred significantly higher in the patient
group in compare with the control group (P value <0.001).
Our finding also revealed the presence of significant
difference between the patient and control group regarding
secondary outcomes including the required blood units
transfusion (P-value <0.001).
Conclusion: We conclude that maternal serum creatine
kinase is not a reliable tool in predicting or diagnosing
placenta accreta.

DOI

10.21608/egyfs.2022.237722

Keywords

Keywords: Creatine kinase, placenta accreta, Previa, Ultrasonography, surgical outcome

Authors

First Name

mohamed

Last Name

eid

MiddleName

ibrahem

Affiliation

mansoura university obstetrics and gynecology dep

Email

dr_moh_eid@yahoo.com

City

-

Orcid

-

Volume

26

Article Issue

2

Related Issue

34259

Issue Date

2022-05-01

Receive Date

2022-05-17

Publish Date

2022-05-01

Page Start

13

Page End

20

Print ISSN

1110-6352

Online ISSN

2536-9768

Link

https://egyfs.journals.ekb.eg/article_237722.html

Detail API

https://egyfs.journals.ekb.eg/service?article_code=237722

Order

3

Type

Original Article

Type Code

319

Publication Type

Journal

Publication Title

The Egyptian Journal of Fertility of Sterility

Publication Link

https://egyfs.journals.ekb.eg/

MainTitle

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Details

Type

Article

Created At

22 Jan 2023