The objective of this study of patients with habitual abortion, was planned to determine their autoimmune profile and to
try to prevent new abortions using low-dose aspirin (Rivo® 75mg) for 7 months with solupred® 20 mg in the first
trimester only, or with low-dose aspirin alone. A total of 100 patients with three or more HA were investigated for
antiphospholipid antibodies, antinuclear and anti thyroid antibodies. Among these patients, auto antibodies were present
in 34% of the patients, in 82.4% of them anticardiolipin antibodies were found to be isolated alone or associated with
lupus anticoagulant, anti thyroid, or, antinuclear antibodies. In auto antibodies-negative pregnant women treated by
solupred and aspirin or aspirin alone, the success rate of live births was 90.9% (30 out of 33) and 75.7% (25 out of 33)
rcspectivley (p < 0.01) in auto antibodies - positive patients treated with solupred and aspirin the success rate was
85.2% (29 out of 34) (not significant) solupred and aspirin seemed to he as efficient in auto antibodies - negative or
positive women but better than aspirin alone in autoantibody - negative women.