Objective: To investigate whether intravenous immunoglobulin (IVIG) can improve the chance of livebirth in women
with a history of recurrent spontaneous miscarriage (RM).
Study design: Randomized, double-blind, placebo- controlled trial.
Patients and interventions: Fifty four women with a history of secondary (RM) were randomly assigned to receive
doses of (IVIG) or placebo (Saline) starting as soon as pregnancy test was positive.
Results: The live birth rate (LBR) was significantly higher in the IVIG group when compared with placebo-infused
group even after exclusion of cases of ectopic pregnancy and cases with low serum ~hCG and progesterone levels,