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267734

Crosstalk between Maternal Life and Fetal Epigenome; A Review Article

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Section B: Pharmaceutical Analytical & Organic Chemistry, Medicinal & Biochemistry

Abstract

Background: It is important to say that maternal lifestyle during gestation could affect embryonic development and health consequences. Objectives: Many endogenous and exogenous factors affect the epigenetics of the germ cells during their division and subsequently affect the embryogenesis. Methods: This systematic review outline various studies that link the different environmental factors and modification in the fetal epigenome. Conclusion: Aberrant fetal epigenome modification subsequently affects the healthy embryonic growth and their contribution to the phenotypic changes and chronic disease development later in life.

DOI

10.21608/aprh.2022.144865.1181

Keywords

Epigenetic modifications, COVID, Histone remodeling, Prenatal health, Radiation

Authors

First Name

Shahenda

Last Name

Mahgoub

MiddleName

-

Affiliation

Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo,11795, Egypt.

Email

shahendamahgoub@gmail.com

City

cairo

Orcid

-

First Name

Hadeer

Last Name

Abosalem

MiddleName

-

Affiliation

Egyptian drug authority (EDA), Giza, 12654, Egypt.

Email

hadeer.abosalem@yahoo.con

City

cairo

Orcid

-

First Name

Dina

Last Name

Mahmoud

MiddleName

-

Affiliation

Egyptian drug authority (EDA), Giza, 12654, Egypt.

Email

dina.mahmoud@yahoo.com

City

cairo

Orcid

-

First Name

Doaa

Last Name

Abdel Mohsen

MiddleName

-

Affiliation

Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo,11795, Egypt.

Email

doaamohamed@pharm.helwan.edu.eg

City

cairo

Orcid

0000-0002-8312-4353

First Name

Zeinab

Last Name

Abd-eltwab

MiddleName

-

Affiliation

Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo,11795, Egypt.

Email

zihassan2008@hotmail.com

City

Cairo

Orcid

-

Volume

6

Article Issue

4

Related Issue

37446

Issue Date

2022-10-01

Receive Date

2022-06-15

Publish Date

2022-10-01

Page Start

181

Page End

191

Print ISSN

2357-0547

Online ISSN

2357-0539

Article File

APRH_Volume 6_Issue 4_Pages 181-191.pdf

PDF . 598.9kB

Link

https://aprh.journals.ekb.eg/article_267734.html

Detail API

https://aprh.journals.ekb.eg/service?article_code=267734

Order

2

Type

Review Article

Type Code

358

Publication Type

Journal

Publication Title

Journal of Advanced Pharmacy Research

Publication Link

https://aprh.journals.ekb.eg/

MainTitle

Crosstalk between Maternal Life and Fetal Epigenome; A Review Article

Details

Type

Article

Created At

22 Jan 2023